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dimethylamino team enormously enhances the MOR affinity, as in U-47700. By contrast, embedding that very same essential nitrogen right into a cyclic pyrrolidine ring greatly boosts the KOR affinity, as in U-50488. MOR/KOR selectivity is affected through the NU-47700 was produced within a lab by 20th-century pharmaceutical huge Upjohn. In 1976, chem

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